Extraocular motoneuron pools develop along a dorsoventral axis in zebrafish, Danio rerio
Both spatial and temporal cues determine the fate of immature neurons. A major challenge at the interface of developmental and systems neuroscience is to relate this spatiotemporal trajectory of maturation to circuit-level functional organization. This study examined the development of two extraocular motor nuclei (nIII and nIV), structures in which a motoneuron's identity, or choice of muscle partner, defines its behavioral role.
Published in the Journal of Comparative Neurology, 2016.